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Are you over 50 and noticing any of these symptoms? Lack of energy. Are you feeling unusually tired and have less energy than you used to? Feeling the cold more easily? You may feel chilly even when others around you are comfortable. Gaining weight despite a decrease in appetite. When your metabolism slows down, fewer calories are required. Noticing that you are losing your appetite —but still putting on more fat. Muscle and Joint pain. Thin Hair and dry nails? Hypothyroidism can cause symptoms throughout the body, from constipation to aching muscles and joint pain. Skin, hair, and nails may become thin and dry. Changes in your ability to concentrate and focus. Hypothyroidism and depression have similar symptoms, like difficulty concentrating,