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Introduction to Bone Function” Osteoporosis is a metabolic condition associated with the skeletal system. The decrease in bone mass density and the demineralization of bones often results in bone fracture. The vertebral column, wrist and hip are the most commonly affected parts of the body. The Role of the Skeletal System The skeletal system has several important functions: First, it provides the framework and shape of the body, allowing it to support weight-bearing activities and hold an upright posture. Second, it supports the surrounding tissues such as the tendons, ligaments and muscles. Third, it assists in movement through muscle attachments and the joints. Other important functions include the protection of vital organs, the manufacturing of essential blood cells and the